Systematic review of hyaluronic acid (HA)-related complications.

Objective:

To systematically review all available literature including case reports and case series to identify a pattern for the management of vascular compromise resulting in facial skin ischemia and ocular manifestations following HA injection.

This review was based on a systematic search of 3 electronic databases PubMed, CINAHL, and Scopus for all available literature including case series and case reports from database inception to July 2019.

Only a total of 52 case reports/series were eligible for review and included 107 patients.

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