Weissman O, Farber N, Remer E, Tessone A, Trivizki O, Bank J, Winkler E, Zilinsky I, Haik J. Post-facelift flap necrosis treatment using charged polystyrene microspheres. Can J Plast Surg. 2013 Spring;21(1):45-7. doi: 10.1177/229255031302100113. PMID: 24431937; PMCID: PMC3891099.

Abstract 

Background: Flap necrosis following facial rhytidectomy constitutes a vexing and grievous complication to the patient and the surgeon. Treatment modalities that can expedite wound healing and re-epithelialization rates are highly desired.

Objectives: To assess wound healing and re-epithelialization rates of open wounds following postrhytidectomy flap necrosis treated with commercially available charged polystyrene microspheres (Polyheal-1, Polyheal Ltd, Israel).

Methods: Flap necrosis following rhytidectomy with open wounds in three female patients were treated using dressings soaked with Polyheal-1. Wound closure rates were documented.

Results: The wounds demonstrated both accelerated granulation tissue formation and rapid re-epithelialization rates. No complications or side effects were encountered.

Conclusions: Charged polystyrene microspheres may offer a new and efficacious way to treat open wounds due to flap necrosis following facial rhytidectomy. Further research with larger patient numbers is still needed to verify these findings.

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