An accurate and comprehensive histopathology report is essential for cutaneous melanoma management, providing critical information for accurate staging and risk estimation and determining the optimal surgical approach.

In many institutions, a review of melanoma biopsy specimens by expert dermatopathologists is considered a necessary step.

This study examined these reviews to determine the critical primary histopathology Breslow score in which a histopathology review would be most beneficial.

Histopathology reports of patients referred to our institute between January 2011 and September 2019 were compared with our in-house review conducted by an expert dermatopathologist.

The review focused on assessing fundamental histologic and clinical prognostic features. A total of 177 specimens underwent histopathology review.

Significant changes in the Breslow index were identified in 103 cases (58.2%). Notably, in many of these cases (73.2%), the revised Breslow was higher than the initially reported score.