In scientific literature, numerous theories on the mechanism of facial aging can be found.

The debate about facial sagging versus deflation is still ongoing. In this study, the metric changes in perioral soft tissue were demonstrated.

These data can contribute to a better understanding of physical changes in the aging perioral area.

Upper lip measurements were performed on cranial magnetic resonance images of 200 Caucasian subjects (100 men and 100 women).

The study population was aged between 20 to 30 and 65 to 80 years.

The upper lip length and soft-tissue thickness were measured on sagittal and parasagittal section. Cross-section surface area of the upper lip was measured in the sagittal section to represent volume.

The data were analyzed with a t test and results were considered significant at p < 0.01.